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Opiate Use and Decreased Hormone Levels



Chronic use of opiates has long been associated with lower levels of androgens. Studies have shown that long-term opiate use may lead to opiate induced hypogonadism, resulting in significantly decreased testosterone levels in men.

The correlation between opiate-induced hypogonadism and associated side effects such as osteoporosis, sexual dysfunction, lack of libido, loss of muscle tone, decrease in muscle mass and strength in male patients has been clearly documented. Marked testosterone deficiency is a well established factor for both osteoporosis and altered sexual function. Recent information demonstrates that opiate use and altered estrogen levels in females may play a role in these side effects as well.

Once the patient is free from the opiate addiction and regains their health, the levels of testosterone and estrogen will return to normal. Supplementation is not advised due to the need to continue the supplement, which does not allow the body to signal it's own natural hormonal production.
 
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