Painkiller 10 times stronger than Vicodin being developed – sparking addiction fears

Drug companies are developing a painkiller ten times stronger than Vicodin which addiction experts fear could spark a wave of abuse. Four companies have begun patient testing on the pills which are the first to contain the addictive ingredient hydrocodone in a pure form. If approved, it would mark the first time patients could legally buy pure hydrocodone as existing products combine the drug with nonaddictive painkillers such as acetaminophen.

The pharmaceutical firms claim the new drug will give doctors another tool to help patients manage pain. The companies also say patients will be more closely supervised. However addiction experts fear abusers will crush the pills into a fine powder and snort it to get high. Such practice is common with the painkiller oxycodone, currently the most-abused medicine in the U.S.

April Rovero, president of the National Coalition Against Prescription Drug Abuse told Fox news: ‘I have a big concern that this could be the next OxyContin. ‘We just don’t need this on the market.’

According to the DEA, there were 19,221 emergency room visits as a result of hydrocodone abuse in 2000. The figure was 86,258 in 2009. Between 2003 and 2007 in the state of Florida alone, hydrocodone caused 910 deaths and contributed to 1,803 others.

Andrew Kolodny, president of Physicians for Responsible Opioid Prescribing told CBS: ‘You’ve got a person on your product for life, and a doctor’s got a patient who’s never going to miss an appointment, because if they did and they didn’t get their prescription, they would feel very sick. Abuse: Addicts crush pills such as oxycodone into a fine powder which they snort to get high. ‘It’s a terrific business model, and that’s what these companies want to get in on.’

The San Diego company Zogenix plans hopes to begin marketing its product, Zohyadro, in early 2013. Rival companies Perdue Pharma, Cephalon, and Egalet are developing their own versions. Zogenix chief executive Roger Hawley claims Zohydro will be a safer painkiller than Vicodin as Vicodin contains acetaminophen which can be dangerous to the liver.

CDC Report on Prescription Painkiller Overdose is a Call To Action

By Grant Baldwin, PhD, MPH November 4, 2011

The CDC (Center for Disease Control), deals with the numbers and statistics affecting the public’s health every day. Rarely do these numbers reveal the full and tragic story they actually represent. The CDC’s report this week on prescription painkiller overdoses is one of these rare instances, confirming a story many of us have heard in communities across America.
Prescription painkillers (drugs like oxycodone, hydrocodone and methadone) killed nearly 15,000 people in 2008—one person every forty minutes. These were husbands and sons, mothers and daughters, often struggling with addiction for months or years before losing their lives. And the problem has never been worse. For every person who died of a prescription painkiller overdose in 1999, nearly four died in 2008. We are in the midst of an epidemic.
But the number of deaths isn’t the whole story. This sharp rise in prescription painkiller overdoses parallels a similarly large increase in painkiller sales. Four times as many prescription painkillers were sold in the U.S. last year than in 1999.
Astonishingly, in 2010 enough painkillers were prescribed to medicate every American adult around-the-clock for a month.
States can support prescription drug monitoring programs—electronic databases that track controlled substance prescriptions, which are promising tools for helping medical professionals identify patients who may be abusing these drugs. Health care providers can follow guidelines for safe painkiller prescribing and screen patients for warning signs of abuse. This is so important because we can reduce the number of people who are abusing and overdosing, while also ensuring that patients with pain are treated safely and effectively.
Individuals can also make an impact. More than half of all people who misuse prescription painkillers report getting their drugs from a family member or friend. Individuals must make sure to use prescription painkillers only as directed and to never share them with others. People should also take care to store their prescriptions safely, dispose of them properly and get help if they have substance abuse problems.
Preventing prescription painkiller overdoses is a CDC priority. The lives impacted by painkiller abuse and overdose can be found everywhere—a father who becomes addicted to painkillers after a work injury and overdoses, a teenager who takes an old bottle of painkillers from a relative’s medicine cabinet or a mother who loses a son to painkillers only to find her other child is also addicted. This week’s CDC report on prescription painkiller overdose is a call to action. This epidemic is affecting our own neighbors and communities. Working together, we can turn the tide and have the numbers tell a different story.

The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence according to a news release by them on 10-12-2010.

Vivitrol, or naltrexone, as it is called generically, is a long-acting form of the drug that is injected once a month intramuscularly. Naltrexone hijacks the brain’s opioid receptors blocking the effects of narcotic drugs such as morphine, heroin, oxycodone, hydromorphone, and other opiates.The purpose of the drug is to prevent relapses, and should be used in conjunction with other treatment modalities such as outpatient therapy, NA/AA if you are into the 12-Steps, and having a network of agencies, friends, and family to help support you in your recovery.

Highest Rate Of Abuse Reported In Oklahoma

A new government report shows the number of overdose deaths from powerful painkillers have more than tripled over a decade.

Prescription painkillers such as OxyContin, Vicodin and methadone contributed to the deaths of nearly 15,000 people in 2008. That’s more than three times the 4,000 deaths in 1999.

According to the Centers for Disease Control and Prevention, nearly 5 percent of Americans ages 12 and older say they’ve abused prescription painkillers. The highest rate of abuse was reported in Oklahoma while the lowest was in Nebraska and Iowa.

Fatal overdoses were more likely in men and middle-aged adults.

The report was released Tuesday by the CDC.

For the complete CDC report visit: : http://cdc.gov/mmwr/

Turning disappointment into joy: From Service Dog to SURFice Dog

I want to share this with our readers. I know this video doesn’t have anything to do with drug addiction, but it is inspiring, very heartwarming and can remind all of us that we are special in some way. That all of us can overcome obstacles by having faith and moving forward while believing in ourselves.

These dear little children no longer have to live with a disfigurement

RDD is grateful for our patient’s trust in us. Our patients can be assured that a portion of their cost of treatment goes to SMILE TRAIN to help poor children around the world with a much needed surgery. These dear little children no longer have to live with a disfigurement.

Dear Jeanne,

After a 20-hour journey, very little sleep the past four nights and four days of non-stop meetings, I’m actually feeling more energized and motivated than ever before!

I traveled to Hyderabad, India to meet with Smile Train international managers and some of our partner surgeons and anesthesiologists who attended a Smile Train-sponsored conference. Over 250 partner-doctors will meet to discuss, evaluate and enhance ways to strengthen our cleft programs to impact more lives than ever before.

This week, our mission came to life in the presence of this esteemed group. Our mission is and continues to be: To empower local medical professionals to provide safe, high-quality and cost-effective cleft treatment for the millions of poor children around the world who suffer from cleft lip and palate.

We’ve just finished a record-breaking third quarter for our fiscal year. Among the highlights, our South Asia region (made up of India, Nepal, Sri Lanka and Bangladesh) had its best quarter ever in the 12-year history of Smile Train, with 13,734 surgeries. This is a 14% increase over last year. And worldwide, we had our 3rd highest quarter ever!

This is a great milestone for everyone here at Smile Train, our partners around the world and really, you, our donors who make this happen.

But our work is not done. Every year more than 170,000 children are born with cleft lips and palates. There’s a huge backlog of children left to help and all of us here at Smile Train are committed to helping every child born with a cleft live a full and productive life.

These surgeries – that take as little 45 minutes – are so important to the children still suffering from cleft lips and palates.

Thank you so much for helping children around the world and giving them a new smile and new life.

All the best,

Priscilla Ma
Executive Director

The Chemical Imbalance Scam

A DANGEROUS COMBINATION: Corrupt Psychiatrists Partnering With Wealthy Pharmaceutical Giants

David B. Stein, Ph.D.
Professor of Psychology and Criminal Justice
Virginia State University

www.drdavestein.com

One of the subjects that I have taught for over twenty-five years is psychopharmacology.  It might be helpful to challenge one of the great myths about mental disorders, namely that they are caused by chemical imbalances.  This myth is founded on some of the tricks that are pulled in so-called scientific research in psychology and psychiatry.  First, there is a large volume of research claiming to discover all kinds of chemical imbalances in a wide variety of psychiatric disorders.  The manipulation of research has become one of the most powerful and most unethical marketing tools ever devised.  Not one study can be replicated at the testing labs of hospitals or by laboratories involved in clinical patient care.  All that one needs to do is ask his or her doctor to order a blood or urine test to confirm any psychiatric disorder, and the response will be, “I’m sorry, but no such test exists.”  Replication is a basic step for all sciences.

The second manipulation is a bit trickier to follow.  An unethical researcher, earning grant money from the pharmaceutical companies, injects test subjects with a radioactive sample of a nervous system hormone, such as dopamine, serotonin, nor-epinephrine, and so on, and then trace, using either CT scans, MRIs, or PET scans, exactly to what parts of the brain the chemicals go.  They can even trace the hormones to microscopic receptor sites on the ends on neurons.  They then repeat the injection process with a radioactive sample of one of the drugs that supposedly correct chemical imbalances, such as antidepressants that elevate serotonin, or amphetamines that effect serotonin and dopamine, and so on and so forth.  By golly the drugs go to the same exact parts of the brain and receptor sites as the hormones.   Conclusion, the drugs are correcting chemical imbalances!

Not so fast.  The part they do not tell the public, and even professional psychiatrists, psychologists, and practicing physicians, is that we can precisely measure hormone levels in all people, and diagnosis does not matter.  We can measure the metabolites in the blood, which are the residue left after the hormones are metabolized i.e. used by the nerve and body cells.  This tells us the precise amount of hormones carried in anyone’s body. When that is done, as it has by numerous honest researchers, we discover that the amount of hormones are exactly the same for anyone with a diagnosis, such as depression, attention deficit disorders (ADD/ADHD), bipolar, and schizophrenia, as with anyone diagnosed as perfectly normal.

There is a third part to the perpetuation of scam information.  We are told that when a drug alleviates certain psychiatric conditions, such as depression and anxiety, that the drug is therefore correcting obvious chemical imbalances.  However, this type of logic is not permitted in true science.  This is called “allopathic logic”, which is a no no.

A quick analogy will help clear this up.  If one drinks alcohol, then one experiences a relief from anxiety.  Alcohol is a drug, a sedative.  Can we say that alcohol clears up chemical imbalances that cause anxiety?  If that were so then the entire human race is running around with chemical imbalances.  The same is true for any drug used for any purpose, such as antidepressants for depression, tranquilizers for anxiety, mood stabilizer drugs for bipolar disorder, and even antipsychotic drugs for schizophrenia.  This type of logic is not permitted within proper scientific circles.  Sadly, proper scientific circles are evaporating within psychiatry and psychology.  Those who are ethical researchers make no such claims.

Dr. David B. Stein is Professor of Psychology and Criminal Justice at Virginia State University. He is a best-selling author, and his books include: Ritalin is Not the Answer: A Drug-free, Practical Program for Children Diagnosed with ADD or ADHD; The Ritalin is Not the Answer Action Guide: An Interactive Companion to the best-selling Drug-Free ADD/ADHD Parenting Program; Unraveling the ADD/ADHD Fiasco: A Guide for Successful Parenting; and Controlling the Difficult Adolescent: The REST Program (Real Economy Program for Teens).

White House official says database needed

When White House drug czar Gil Kerlikowske recently toured Appalachia, he met with 14 imprisoned women who were in drug treatment, 13 of whom were being treated for prescription-drug use.

Kerlikowske asked the women how many had been to Florida to get their drugs. “Thirteen of the 14 raised their hand,” Kerlikowske said.

So it may be no surprise that Kerlikowske has an interest in what Florida — considered a key supply source for prescription drugs — does to help solve the problem.

The debate over how to tackle the prescription-drug problem in Florida was renewed last month when Gov. Rick Scott proposed eliminating the Prescription Drug Monitoring Program, a database touted as one of the best tools for fighting prescription drug abuse.

Kerlikowske was in Florida last week and spoke with the Orlando Sentinel

Q: Florida officials say the state is a key supplier of prescription drugs. Is this accurate?

A: Oh, yeah. Not only the data — about where people are dying and where they’re overdosing — but where the pills come from. They’re being issued in Florida, they’re being filled in Florida. I think it’s absolutely accurate. Unfortunately, Florida is a key supplier.

Q: Do you think Florida should implement its Prescription Drug Monitoring Program?

A: Yes. Absolutely. We don’t claim — and I don’t think anybody claims — it’s an end-all and be-all to the prescription-drug problem. But when you look at approaching this problem, you’ve got to approach it holistically. This is just one of those tools. The PDMPs are a good start.
Q: Your office has said prescription-drug abuse is the fastest-growing drug problem in the U.S. How does this compare with other drug problems?

A: In the big picture, it really does stand out greater in many ways. Look at the number of deaths. It’s greater than heroin and cocaine overdose deaths combined. In 17 states, it’s greater than car crashes. In those 17 states it would be the No. 1cause of accidental death.

If there was a headline that said Toyota Priuses were responsible for 36,000 deaths a year, there would be a huge outcry. And yet, this one is very difficult.

Q: What makes prescription abuse different from abuse of other drugs?

A: People don’t recognize the danger of prescription drugs. When I was in Appalachia, they often talked about sharing drugs. There are a lot of people from the agriculture industry and mining industry who have injuries, and they would be prescribed prescription drugs. Someone else would have an injury, and that drug would be shared. It was a pretty common thing.

These are pharmaceuticals. I think it really does make it a much harder epidemic … to combat. That’s why prevention is going to be the key, not just trying to shut down pain clinics.

Shocking Statistics About Opiate Use

Since 1990, there has been a tenfold increase in prescriptions for opioids in the U.S., according to the Centers for Disease Control and Prevention (CDC). In 2007, 3.7 million people filled 21 million legal prescriptions for opioid painkillers, and 5.2 million people over the age of 12 reported using prescription painkillers nonmedically in the previous month, according to a survey by the Substance Abuse and Mental Health Services Administration (SAMHSA). From 2004 to ‘08, emergency-room visits for opioid misuse doubled. At the same time, the drugs have become the stuff of pop culture, gaining cachet in the process. The fictitious Dr. House and Nurse Jackie gobble them like gumdrops, as did the decidedly nonfictional Rush Limbaugh and Heath Ledger. And, like Ledger, some users don’t make it out alive.

In 1990 there were barely 6,000 deaths from accidental drug poisoning in the U.S. By 2007 that number had nearly quintupled, to 27,658. In 15 states and the District of Columbia, unintentional overdoses have, for the first time in modern memory, replaced motor-vehicle incidents as the leading cause of accidental death; and in three more states it’s close to a tie.

More babies born addicted to pain drugs

Florida’s prescription drug epidemic, already responsible for nearly seven deaths a day, is taking its toll on the youngest, most vulnerable in our communities: newborns.

In 2009, nearly 1,000 babies born in Florida hospitals were treated for drug withdrawal syndrome. They’re irritable. They don’t eat well. They can spend days, even weeks, detoxing.

And the number is skyrocketing.

Janet Colbert, a registered nurse in a neonatal intensive care unit at a Broward County hospital, witnesses with alarming frequency the heartbreaking physical trauma these newborns endure.

“I kept seeing the torture these babies are going through,” said Colbert, 59, of Dania Beach. “This one baby, he couldn’t even feed. He was screaming, his face was just quivering so badly he couldn’t even get his face around the nipple to feed — and I just said I have to do something.”

Last spring, Colbert and two other women, also healthcare professionals, founded the STOPP Now organization (Stop the Organized Pull Pushers). They stage monthly protests at certain Broward County pain clinics they consider to be pill mills doling out excessive quantities of narcotic painkillers.

From 2006 to 2009, there was a 173 percent increase in newborns treated at Florida hospitals for drug withdrawal syndrome, according to Agency of Health Care Administration records obtained by the Orlando Sentinel.

The most recent data show no signs of a slowdown. During the first half of 2010, 635 cases were reported.

While the state records don’t specify which narcotics those babies tested positive for, South and Central Florida doctors say a majority of the withdrawal cases involve prescription drugs.

“We see them here almost daily,” said Dr. Matthew Seibel, a pediatric hospitalist at Arnold Palmer Hospital for Children and Winnie Palmer Hospital for Women & Babies. “It is standard operating procedure around here, unfortunately.”

Infants suffer

It used to be that infants born with drug withdrawal symptoms were more likely to be suffering from a crack cocaine addiction.

But doctors, nurses and social workers say cases of “crack babies” are dwindling, while cases of prescription drug dependence are becoming more prevalent.

Colbert, the nurse, said more often than not the babies at her hospital are testing positive for oxycodone and other prescription drugs.

Former state Sen. Dave Aronberg, a Palm Beach County attorney now leading Attorney General Pam Bondi’s new anti-pill mill initiative, called the newborn drug withdrawal statistics “horrifying.”

“Prescription drug abuse has become the number one public safety threat to Florida,” he said.

State child-welfare officials in Central Florida have taken notice of the surge. The problem was escalating so much in Orange County that in 2008, the local Department of Children and Families office reinstituted its Drug Dependent Newborn unit. It’s the only DCF unit in the state dedicated to serving newborns dependent on drugs.

Last year, the unit received 206 cases.

In South Florida, all the hospitals with delivery rooms see babies born addicted to painkillers, nurses said. Fifty-five were born addicted to some substance — the state doesn’t break out painkillers — in the first half of last year in Broward and Palm Beach counties, up sharply from 29 in all of 2006, state figures show.

From her experience, Colbert said, those numbers sound low. That may be because some doctors classify cases as maternal drug abuse rather than neonatal drug abuse, she said.

Hospitals prefer to keep addicted babies for at least four weeks to gradually wean them off drugs, rather than send them home to detox, said registered nurse Mary Osuch, manager of the neonatal intensive care unit at Broward General Medical Center in Fort Lauderdale.

“If we don’t intervene, they are more vulnerable to child abuse because they are inconsolable and the parents can’t take it after a while,” Osuch said.

The drugs steal their appetites and cause stomach cramps. When the babies do eat, they get diarrhea. They don’t rest well. And they are irritable all the time, Osuch said.

“It’s so hard to watch them,” Osuch said. “You can’t console them.”

Typically, NICU doctors give addicted babies the sedative phenobarbital to ease the withdrawal, Osuch said. If that doesn’t work, they use methadone or even morphine. Over days or weeks, they reduce the dosage until the baby is drug free and eating and sleeping normally.

Mothers are steered toward parenting classes, counseling and assistance with scheduling doctors appointments and follow-up care for the newborn.

Mores seek treatment

At the Center for Drug Free Living’s Addictions Receiving Facility near downtown Orlando, the number of people being treated for prescription drug abuse — including pregnant women — is on the rise.

Doctors have treated pregnant women with methadone, often prescribed in place of oxycodone for pain management, since the 1960s.

That method still stands today, because women who abuse drugs like oxycodone cannot go cold-turkey while they are pregnant. Doctors say it’s too stressful on the mother’s body, which imposes stress on the developing baby.

Doctors would rather have a steady level of methadone in the developing baby than a mother who takes other drugs, explained Dr. Stacy E. Seikel, medical director at the center.

“When the mother is in withdrawal, the baby is in withdrawal,” she said. “If the baby is in and out of withdrawal the entire pregnancy … the baby can’t grow and mature well.”

‘Prescription nation’

Officials say the increase in drug-dependent newborns is further evidence of Florida’s — and the nation’s — growing use of prescription drugs.

Drug addicts and dealers from northern states, dubbed “pillbillies,” travel to Florida, where a plethora of pain clinic doctors are willing to dole out addictive, powerful painkillers and sedatives like oxycodone and alprazolam.

From October 2008 to March 2009, 49 of the nation’s top 50 dispensing doctors of oxycodone were in Florida, with the majority concentrated in Broward and Palm Beach counties, a grand jury reported. And according to one national study, the use of prescription pain medication increased 400 percent from 1998 to 2008.

Colbert, the neonatal nurse, says every time she tries to comfort yet another inconsolable newborn through withdrawals, she wonders why politicians allow the abuse to continue.

“It’s like a side effect no one’s seeing,” she said. “Every time we admit another baby like this, I wonder, why isn’t somebody doing something about this.”

Sen. Mike Fasano, R-New Port Richey, who has been a state leader in the pill mill fight, said he was unaware of this aspect of the prescription drug scourge.

“You don’t realize how there’s that trickle-down effect,” Fasano said. “This is another perfect example of why we have to address this crisis in Florida, this epidemic.”